Does residual K562 affect the functionality of expanded immune cells?

Multidimensional studies by Hillgene have shown that after 14 days of co-culture with NK cells, the residual K562 rate is below 0.1%.

This low level of residual K562 does not significantly affect the viability, cytotoxic function, or multifunctional cytokine secretion of NK cells or other immune cells such as TILs.

Therefore, using Hillgene’s K562 feeder cell system for expansion ensures both safety and functional integrity, making it suitable for large-scale in vitro immune cell production.